Novak Djokovic defated in Australian Open 2nd round by world number 117
The Serb was defeated in the match by 7-6 (10-8) 5-7 2-6 7-6 (7-5) 6-4 margin.
It took four hours and 48 minutes for Denis Istomin to clinch the match and register a major upset in the tournament this year.
This was the first time since Novak was defeated in the second round of a major tournament since 2008 at Wimbledon.
His defeat left Britain's Andy Murray as one of the favourites to win the trophy.
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