Paris: Four-time Grand Slam champion Naomi Osaka of Japan suffered an opening round exit from the French Open after losing to America's Amanda Anisimova on Monday.
Anisimova defeated Osaka 7-5, 6-4 in 1 hour and 30 minutes.
At the Australian Open in January, Anisimova saved two match points before ousting Osaka 4-6, 6-3, 7-6 (5) in the third round.
The first three games of the contest went against serve before Anisimova consolidated her advantage for a 3-1 lead.
The Japanese star broke back though, drawing level two games later. The pair remained neck and neck until Anisimova broke to edge ahead 6-5. The 20-year-old American wrapped up the set 7-5 on the 46-minute mark.
Anisimova made her move in game seven of the second set, and despite seeing two match points slip as she was serving for the win, she fired a signature down-the-line backhand to secure passage to round two.
The American will play Croatian qualifier Donna Vekic in the second round.
(With UNI inputs)